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Image Search Results
Journal: Oxidative Medicine and Cellular Longevity
Article Title: Exercise-Induced Changes in Caveolin-1, Depletion of Mitochondrial Cholesterol, and the Inhibition of Mitochondrial Swelling in Rat Skeletal Muscle but Not in the Liver
doi: 10.1155/2016/3620929
Figure Lengend Snippet: Mitochondrial cholesterol levels in controlled and exercised animals. Cholesterol was measured in crude mitochondria isolated from the quadriceps (a) and liver (b). The data are presented as the means ± SE. ∗ There was a significant difference between the E (exercise) versus C (control) in the Quadriceps mitochondria ∗ P = 0.001 versus the control rats ( n = 6 in each group).
Article Snippet: The
Techniques: Isolation, Control
Journal: Oxidative Medicine and Cellular Longevity
Article Title: Exercise-Induced Changes in Caveolin-1, Depletion of Mitochondrial Cholesterol, and the Inhibition of Mitochondrial Swelling in Rat Skeletal Muscle but Not in the Liver
doi: 10.1155/2016/3620929
Figure Lengend Snippet: Correlation between caveolin-1 and cholesterol levels in quadriceps crude mitochondria. A Pearson product-moment correlation coefficient was computed to assess the relationship between the caveolin-1 and cholesterol level in the crude mitochondria isolated from the quadriceps. There was a large, negative correlation between the two variables, r = −0.67, P = 0.017.
Article Snippet: The
Techniques: Isolation
Journal: Oxidative Medicine and Cellular Longevity
Article Title: Exercise-Induced Changes in Caveolin-1, Depletion of Mitochondrial Cholesterol, and the Inhibition of Mitochondrial Swelling in Rat Skeletal Muscle but Not in the Liver
doi: 10.1155/2016/3620929
Figure Lengend Snippet: The Cav-1-dependent hypothesis of mitoprotection under exercise conditions. Under physiological conditions: appropriate levels of Cav-1 and cholesterol concentrations are presented in the mitochondria of contractile tissues. Under pathological conditions in crude mitochondria, decreased Cav-1, increased cholesterol concentrations, and mitochondrial swelling are observed. Exercise induces the opposite effects; for example, increased Cav-1 levels and decreased cholesterol levels in mitochondria lead to the inhibition of mitochondria swelling.
Article Snippet: The
Techniques: Inhibition